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Eric Nawrocki edited this page Sep 16, 2026
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VADR wiki
VADR (Viral Annotation DefineR) is a tool for validation and annotation of virus
sequence submissions to GenBank.
Use the sidebar to navigate. This wiki covers:
Annotation guides — how to run VADR for SARS-CoV-2, influenza, mpox virus,
RSV and Zika virus.
GenBank processing versions — which VADR version, models and command-line
options GenBank has used, and when, for the viruses it processes
automatically.
Models and reference — available model files and download instructions,
Rfam-based structural annotation of a viral genome sequence, and development
notes.